16 Years Later, Castiel's Best Line Is Still A Top 3 Supernatural Quote

For 15 seasons, Supernaturalprovided some of the funniest, most iconic TV quotes, including Castiel's best line of the series, which even 16 years later has become a series-best. Throughout the run of Supernatural, Dean Winchester (Jensen Ackles) and his brother Sam (Jared Padalecki) made their way across the US to take down demons and monsters, all while contending with the doom and gloom of the impending apocalypse. With help from others, like angel Castiel (Misha Collins), the brothers went to hell and back over and over, which separated them countless times, but they always found their way back together.