The Sopranos is not only one of the biggest TV shows of all-time, but it's still nearly as popular today as it was when it debuted over a quarter of a century ago. Movies and TV series centered around mob bosses and organized crime had been done countless times, but David Chase's The Sopranos felt different because it dug deeper into the emotions of its characters. Tony's (James Gandolfini) anxiety and depression are often at the heart of the action. Even scenes of him simply speaking to his therapist, Dr. Melfi (Lorraine Bracco), could be highly captivating.