A clearer image of glaucoma: The relationship between unfolding and aggregation for glaucoma-associated myocilin

From Parkinson's and Alzheimer's to cardiac arrhythmia, amyloids are linked to a number of diseases. These aggregates of proteins form in the body when a protein loses its normal structure and misfolds or mutates. And since many of these proteins are large and complicated, just how some of these mutations occur and aggregate remains a mystery—as does the creation of effective treatments.