1000-lb Sisterspremiered in 2020 and followed Amy and Tammy Slaton’s grueling yet heartwarming weight loss journey. Over the years, the sisters have come pretty far. Starting from their respective weight loss surgeries, the show has chronicled all of their ups and downs. But as much as the show has focused on their individual transformations, it’s also evolved into something more expansive that now centers around the broader Slaton family dynamics.