Since making his television debut, 1000-lb Sisters star Chris Combs has lost weight and significantly improved his health. The show chronicles the weight-loss journeys of Amy Slaton and Tammy Slaton, but several of their siblings have also gotten involved, including 44-year-old Chris. It can't be overstated how far Chris has come over the years, and how much he has changed his life. Chris struggled with weight his whole life, and the problem followed him into his adulthood. His weight was a lifelong enemy. It caused health problems and lowered his quality of life.