The One Chicago universe has experienced many significant losses across all series, but some have been more devastating than others. Heading into the 2025–2026 network TV season, NBC's popular franchise (which includes Chicago Fire, Chicago PD, Chicago Med, and Chicago Justice) has produced 36 seasons and almost 730 episodes, and it's showing no signs of stopping. With more seasons and episodes on the way, there are sure to be many more heartbreaking departures, given the nature of the three current shows.